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| Life cycle of Plasmodium falciparum |
“In this article we have attempted to make the case that we may not know enough about malaria to make an effective vaccine. If we agree that the development of a malaria vaccine would profit from a better understanding of the basic immunology of the human response to malaria, we then need to ask the following question: have we engaged a sufficient number of immunologists to address the problem? At the moment, probably not. Relative to the magnitude of the global disease burden imposed by malaria, there are only a small number of scientists with the training and expertise in the human immune system who are committed to working at the molecular interface of the parasite and the immune system.”
— Pierce, S., & Miller, L. (2009). World Malaria Day 2009: What Malaria Knows about the Immune System That Immunologists Still Do Not The Journal of Immunology, 182 (9), 5171-5177 DOI: 10.4049/jimmunol.0804153
