As the overwhelming majority of the mutations in cancer cells are unrelated to malignancy, the mutation-generated epitopes shall be specific for each individual tumor, and constitute the antigenic fingerprint of each tumor. These calculations highlight the benefits for personalization of immunotherapy of human cancer, and in view of the substantial pre-existing antigenic repertoire of tumors, emphasize the enormous potential of therapies that modulate the anti-cancer immune response by liberating it from inhibitory influences.

–Srivastava N, Srivastava PK (2009)
Modeling the Repertoire of True Tumor-Specific MHC I Epitopes in a Human Tumor.
PLoS ONE 4(7): e6094. doi:10.1371/journal.pone.0006094

(My emphasis)

(See many of my previous posts here for more information)