A new technique called optical frequency domain imaging (OFDI) provides amazing images of tumors (especially their blood vessels) in situ.
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| “(a) OFDI images of representative control and treated tumors 5 d after initiation of antiangiogenic VEGFR-2. The lymphatic vascular networks are also presented (blue) for both tumors. (b) Quantification of tumor volume and vascular geometry and morphology in response to VEGFR-2 blockade.” |
— Vakoc, B., Lanning, R., Tyrrell, J., Padera, T., Bartlett, L., Stylianopoulos, T., Munn, L., Tearney, G., Fukumura, D., Jain, R., & Bouma, B. (2009). Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging Nature Medicine DOI: 10.1038/nm.1971
