Comments on: Viruses and icebergs http://www.iayork.com/MysteryRays/2009/09/30/viruses-and-icebergs/ Meddling with things mankind is not meant to understand. Also, pictures of my kids Sat, 25 Jun 2011 18:45:54 +0000 hourly 1 http://wordpress.org/?v=3.3 By: Jamie Roux http://www.iayork.com/MysteryRays/2009/09/30/viruses-and-icebergs/comment-page-1/#comment-177538 Jamie Roux Tue, 03 May 2011 20:05:47 +0000 http://www.iayork.com/MysteryRays/?p=1419#comment-177538 In the field of viruses and bacteria metagenomics are revealing exactly how little we still know. It's simply mindblowing. Fortunately most of these newly discovered creatures are harmless. In the field of viruses and bacteria metagenomics are revealing exactly how little we still know. It’s simply mindblowing. Fortunately most of these newly discovered creatures are harmless.

]]> By: Short takes: Deep sequencing and HIV drug resistance | Science Report | Biology News, Economics News, Computer Science News, Mathematics News, Physics News, Psychology News http://www.iayork.com/MysteryRays/2009/09/30/viruses-and-icebergs/comment-page-1/#comment-51058 Short takes: Deep sequencing and HIV drug resistance | Science Report | Biology News, Economics News, Computer Science News, Mathematics News, Physics News, Psychology News Mon, 12 Jul 2010 22:58:47 +0000 http://www.iayork.com/MysteryRays/?p=1419#comment-51058 [...] The whole deep sequencing thing is going to profoundly change our knowledge of viral pathogenesis, as well as their ecology. [...] [...] The whole deep sequencing thing is going to profoundly change our knowledge of viral pathogenesis, as well as their ecology. [...]

]]> By: Short takes: Deep sequencing and HIV drug resistance | Mystery Rays from Outer Space http://www.iayork.com/MysteryRays/2009/09/30/viruses-and-icebergs/comment-page-1/#comment-51016 Short takes: Deep sequencing and HIV drug resistance | Mystery Rays from Outer Space Mon, 12 Jul 2010 10:15:38 +0000 http://www.iayork.com/MysteryRays/?p=1419#comment-51016 [...] The whole deep sequencing thing is going to profoundly change our knowledge of viral pathogenesis, as well as their ecology. [...] [...] The whole deep sequencing thing is going to profoundly change our knowledge of viral pathogenesis, as well as their ecology. [...]

]]> By: bayman http://www.iayork.com/MysteryRays/2009/09/30/viruses-and-icebergs/comment-page-1/#comment-34232 bayman Thu, 08 Oct 2009 23:29:10 +0000 http://www.iayork.com/MysteryRays/?p=1419#comment-34232 I too find this field very intriguing, but have trouble seeing the path to biological meaning. How much of this stuff is garbage...degraded, free-floating nucleic acid? How do we know any of it is from viruses? Maybe there's and RNA world happening before our eyes? How many of these novel "viruses'" existence has been validated by some independent methodology, even sequence specific PCR for example? Thanks for the turtle papilloma paper. Loving that one right now... I too find this field very intriguing, but have trouble seeing the path to biological meaning. How much of this stuff is garbage…degraded, free-floating nucleic acid? How do we know any of it is from viruses? Maybe there’s and RNA world happening before our eyes?

How many of these novel “viruses’” existence has been validated by some independent methodology, even sequence specific PCR for example?

Thanks for the turtle papilloma paper. Loving that one right now…

]]> By: iayork http://www.iayork.com/MysteryRays/2009/09/30/viruses-and-icebergs/comment-page-1/#comment-34200 iayork Thu, 08 Oct 2009 01:10:10 +0000 http://www.iayork.com/MysteryRays/?p=1419#comment-34200 Kay - I should go back and double-check that (I had an answer when I read the papers but I don't remember what it was ... ) but I've been giving and marking exams all week, and tomorrow I'm "chaperoning" an all-day school trip with my son; so no time. One point was, as I recall, that these were RNA genomes, meaning viruses; but how they knew they were genomes and not mRNA I don't remember. Kay – I should go back and double-check that (I had an answer when I read the papers but I don’t remember what it was … ) but I’ve been giving and marking exams all week, and tomorrow I’m “chaperoning” an all-day school trip with my son; so no time. One point was, as I recall, that these were RNA genomes, meaning viruses; but how they knew they were genomes and not mRNA I don’t remember.

]]> By: kay http://www.iayork.com/MysteryRays/2009/09/30/viruses-and-icebergs/comment-page-1/#comment-34129 kay Tue, 06 Oct 2009 00:22:12 +0000 http://www.iayork.com/MysteryRays/?p=1419#comment-34129 At the risk of looking really stupid: if these sequences are totally unrelated to anything known - how do the metagenomics folks know they are of viral origin ? At the risk of looking really stupid: if these sequences are totally unrelated to anything known – how do the metagenomics folks know they are of viral origin ?

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