Peer-reviewed papers & invited reviews

1. Georgiadou D, Hearn A, Evnouchidou I, Chroni A, Leondiadis L, York IA, Rock KL, Stratikos E. (2010) Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1. J Immunol. 185(3):1584-92
2. Dang Y, Wang X, York IA, Zheng YH. (2010) Identification of a critical T[Q/D/E]x₅ADx₂[I/L] motif from primate lentivirus Vif proteins that regulate APOBEC3G and APOBEC3F neutralizing activity. J Virol. 2010
3. Hearn A, York IA, Bishop C., Rock KL (2010) Characterizing the Specificity and Cooperation of Aminopeptidases in the Cytosol and Endoplasmic Reticulum during MHC Class I Antigen Presentation. J. Immunol 184:4725-32.
4. Dang Y, Davis RW, York IA, Zheng YH (2010) Identification of ⁸¹LGxGVxIxW⁸⁹ and ¹⁷¹EDRWN¹⁷⁵ domains from human immunodeficiency virus type 1 virus Vif that regulate APOBEC3G and APOBEC3F neutralization activity. J. Virol. 84:5741-50.
5. Dang Y, Wang X, Zhou T, York IA, Zheng YH (2009) Identification of a novel WxSLVK motif in the N terminus of human immunodeficiency virus and simian immunodeficiency virus Vif that is critical for APOBEC3G and APOBEC3F neutralization. J Virol 83:8544-8552.
6. Hearn A, York IA, Rock KL (2009) The Specificity of Trimming of MHC Class I-Presented Peptides in the Endoplasmic Reticulum. J Immunol 183:5526-5536.
7. Kawahara M, York IA, Hearn A, Farfan D, Rock KL (2009) Analysis of the Role of Tripeptidyl Peptidase II in MHC Class I Antigen Presentation In Vivo. J Immunol 183:6069-6077.
8. Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL (2008) Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections. J Immunol 180:1704-1712.
9. Towne CF, York IA, Watkin LB, Lazo JS, Rock KL (2007) Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses. J Immunol 178:6923-6930.
10. York IA, Bhutani N, Zendzian S, Goldberg AL, Rock KL (2006) Tripeptidyl peptidase II is the major peptidase needed to trim long antigenic precursors, but is not required for most MHC class I antigen presentation. J Immunol 177:1434-1443.
11. York IA, Brehm MA, Zendzian S, Towne CF, Rock KL (2006) Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A 103:9202-9207.
12. Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL (2005) Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation. J Immunol 175:6605-6614.
13. York IA, Grant EP, Dahl AM, Rock KL (2005) A mutant cell with a novel defect in MHC class I quality control. J Immunol 174:6839-6846.
14. Rock KL, York IA, Goldberg AL (2004) Post-proteasomal antigen processing for major histocompatibility complex class I presentation. Nat Immunol 5:670-677.
15. York IA, Mo AX, Lemerise K, Zeng W, Shen Y, Abraham CR, Saric T, Goldberg AL, Rock KL (2003) The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation. Immunity 18:429-440.
16. Saric T, Chang SC, Hattori A, York IA, Markant S, Rock KL, Tsujimoto M, Goldberg AL (2002) An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat Immunol 3:1169-176.
17. York IA, Chang SC, Saric T, Keys JA, Favreau JM, Goldberg AL, Rock KL (2002) The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. Nat Immunol 3:1177-184.
18. Rock KL, York IA, Saric T, Goldberg AL (2002) Protein degradation and the generation of MHC class I-presented peptides. Adv Immunol 80:1-70.
19. Russell HI, York IA, Rock KL, Monaco JJ (1999) Class II antigen processing defects in two H2d mouse cell lines are caused by point mutations in the H2-DMa gene. Eur J Immunol 29:905-11.
20. York IA, Goldberg AL, Mo XY, Rock KL (1999) Proteolysis and class I major histocompatibility complex antigen presentation. Immunol Rev 172:49-66.
21. York IA, Rock KL (1996) Antigen processing and presentation by the class I major histocompatibility complex. Annu Rev Immunol 14:369-396.
22. Tomazin R, Hill AB, Jugovic P, York I, van Endert P, Ploegh HL, Andrews DW, Johnson DC (1996) Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP. EMBO J 15:3256-3266.
23. York IA (1996) Immune evasion strategies of the herpesviruses. Chem Biol 3:331-335.
24. Hill A, Jugovic P, York I, Russ G, Bennink J, Yewdell J, Ploegh H, Johnson D (1995) Herpes simplex virus turns off the TAP to evade host immunity. Nature 375:411-415.
25. York IA, Johnson DC (1995) in Viroceptors, Virokines and Related Immune Modulators Encoded by DNA Viruses, ed McFadden G (R.G. Landes Co, Austin, TX), pp 89-110.
26. Levatte M, Weaver L, York I, Johnson D, Dekaban G (1995) Delivery of a foreign gene to sympathetic preganglionic neurons using recombinant herpes simplex virus. Neuroscience 66:737-750.
27. York IA, Roop C, Andrews DW, Riddell SR, Graham FL, Johnson DC (1994) A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes. Cell 77:525-535.
28. York IA, Johnson DC (1993) Direct contact with herpes simplex virus-infected cells results in inhibition of lymphokine-activated killer cells because of cell-to-cell spread of virus. J Infect Dis 168:1127-1132.
29. York IA, Thorsen J (1992) Evaluation of a subunit vaccine for bovine adenovirus type 3. Am J Vet Res 53:180-183.